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Gelation occurs at body temperature, followed by release of the local anesthetics, lidocaine and prilocaine. In addition, o-Toluidine can cause the formation of methemoglobin (metHb) following treatment with prilocaine. 5 g Oraqix®, the mean (±SD) lidocaine and prilocaine Cmax values were 182 (±53) and 77 (±27) ng/mL, respectively. lidocaine and prilocaine can cause serious side effects, especially in children, if any of it gets into the mouth or is swallowed. prilocainePrilocaine is reported as an ingredient of Xylonest mit Adrenalin in Germany. No studies in the intravenous pharmacokinetics of prilocaine in elderly patients have been performed.
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